Harnessing Regulatory T (TReg) Cells to Transform Autoimmune Disease Treatment
Decades of research have revealed a critical insight: Immune system dysfunction in autoimmune diseases isn’t just about overactivity—it’s about imbalance. Sonoma Biotherapeutics is leading the way in restoring that balance through cell therapy, leveraging discoveries made by co-founder and CEO Jeff Bluestone, Ph.D., over the past 20+ years at UC San Francisco. His groundbreaking work on the IL-2 pathway and TReg cells now drives Sonoma’s mission to create durable, disease-modifying treatments.
By expanding and enhancing a patient’s own TReg cells, Sonoma is developing therapies that don’t just suppress symptoms but instead reset immune equilibrium. With a deep commitment to scientific innovation and collaboration, Sonoma is working to bring this new class of medicine to patients, overcoming the complexities of scaling cell therapies and ushering in a new chapter in autoimmune treatment.

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